Thrombectomy vs. medical management for large vessel occlusion strokes with minimal symptoms

نویسندگان

چکیده

Patients with acute ischemic stroke (AIS) presenting mild symptoms a low National Institutes of Health Stroke Scale (NIHSS) score ≤8 and also found to have an intracranial large vessel occlusion (LVO) undergo endovascular thrombolysis (ET) or medical management alone. The current study aimed evaluate the safety effectiveness vs. ET therapy among patients AIS (NIHSS ≤8) accompanied by LVO. present meta‑analysis included articles involving AIS, LVO, thrombectomy/ET alone published in full‑text form (from 1980 2022). Collected variables included: First author name, covered period, publication year, total number age, males, presence diabetes mellitus, hypertension, atrial fibrillation, prior stroke, location, NIHSS admission, modified Rankin scale, bleeding, morbidity mortality. After initial search applying all exclusion inclusion criteria, eight were left final article pool. who underwent was 569, compared 1097 for LVO strokes minimal symptoms. findings point out that may be associated high risk bleeding mortality ≤8).

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Too good to intervene? Thrombectomy for large vessel occlusion strokes with minimal symptoms: an intention-to-treat analysis.

INTRODUCTION The minimal stroke severity justifying endovascular intervention remains elusive; however, a significant proportion of patients presenting with large vessel occlusion (LVO) and mild symptoms subsequently decline and face poor outcomes. OBJECTIVE To evaluate our experience with these patients by comparing best medical therapy with thrombectomy in an intention-to-treat analysis. ...

متن کامل

New Cerebral Microbleeds After Mechanical Thrombectomy for Large-Vessel Occlusion Strokes

The interval appearance of cerebral microbleeds (CMBs) after endovascular treatment has never been described. We investigated the frequency and predictors of new CMBs that developed shortly after mechanical thrombectomy for acute ischemic stroke, and its impact on clinical outcome.We retrospectively analyzed patients with large-vessel occlusion strokes treated with Merci Retriever, Penumbra Sys...

متن کامل

Endovascular treatment for ischemic strokes with large vessel occlusion: proven therapy and bright future.

I ntravenous tissue-type plasminogen activator (tPA) has been the mainstay and only therapy with proven clinical benefit in patients with acute ischemic stroke for the nearly 20 years. 1 Patients harboring a large vessel occlusions (LVOs) seemed to be recalcitrant to intravenous thrombolysis that portended a poor neurological recovery. 2 Catheter-based treatments offered a promise of higher rec...

متن کامل

Endovascular Management of Stroke Patients with Large Vessel Occlusion and Minor Stroke Symptoms

Endovascular mechanical thrombectomy for stroke patients with large vessel occlusion (LVO) in the anterior circulation has become the standard of care based on several major randomized clinical trials. The successful result reported by these trials constitutes what may be the largest achievement in the history of neurological sciences. However, most of these mechanical thrombectomy trials (exce...

متن کامل

Switching strategy for mechanical thrombectomy of acute large vessel occlusion in the anterior circulation.

BACKGROUND AND PURPOSE We introduce the concept of a switching strategy for mechanical thrombectomy with period-to-period analysis. In period 1, forced arterial suction thrombectomy with a Penumbra reperfusion catheter was performed, even in difficult cases; in period 2, forced arterial suction thrombectomy was initially performed, with switching to Solitaire in difficult cases. METHODS We an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2023

ISSN: ['1792-0981', '1792-1015']

DOI: https://doi.org/10.3892/etm.2023.12076